Kim's Reflection: p53 genes, vital in development

The articles were interesting as well as thought provoking. I thought they were good choices for our service learning project and helped in thinking beyond just cancer, and more towards the different facets of it. Some parts of the paper were a bit difficult to read, but was doable. P53 genes function at conserving stability by preventing genome mutation. Nevertheless, it is hypothesized that the p53 play an important role in neoplastic development. Its interesting to find that a person inherits only one functional copy of this important gene from their parents and through the mutation of this gene, it may lead to life-threatening diseases. From the Lee and Bernstein article, it states that it is unclear how the p53 mutations lead to neoplastic development, however; I found it a bit trivial to study the p53 gene in mice. Would continuing to study mice help in being able to control these genes? Are the p53 gene in mice similar to humans, if so to what degree? The paper, written by Lee and Bernstein was written in 1993, are there any new studies that show any different data or promising data that is able to control this gene?