2. What effect might inbreeding have on this disorder?
A number of extrinsic and intrinsic factors contribute to the development of cancer, a disease still far from satisfactorily controlled in most communities worldwide. Studies have shown that cancer are possibly caused by both recessive and or dominant genes. Furthermore, inbreeding leads to an increase in homozygosity of a population. It also may result in a significantly higher phenotypic expression of deleterious recessive genes. One would think that inbreeding would decrease genetic variance and positive heritability. With this, inbreeding would cause an increase of the likelihood of cancer due to the reduction of genetic diversity. It would also cause a variance of susceptibility of diseases and a weaker immune system to fight the cancer cells.
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1 comment:
Great answers! I am pleased that you found the heritability paper in Nature - very helpful.
The final blog entry will simply involve logging in your group's progress on the project before your presentation.
Well done!
Dr. Walker
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