Monday, April 14, 2008

P53 Article Relection ~ Brice Austin

I found the articles interesting; although, confusing at times. The main "take-home" point, I belive, is that the transgenic p53 mutations can cause cancerous tumors. P53 is responsible for neoplastic deveopment. This means that they create many other regulatory genes. In mice the wild type p53 protein keeps the p53 gene from mutating, lessening results tumors. Is there anything similar to this protein in humans? Commonly tumors still develop because the p53 tarnsgenic form still suppreses the activity of the wild type protein. Can the protein be added to or made stronger?

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